At Senvera Therapeutics, our approach centers on a deep foundational understanding of the molecular mechanisms that regulate peripheral olfactory stem cells.
 

We constantly lose olfactory neurons due to a number of causes including aging and viral infection. 

A population of stem cells named Globose Basal Cells (GBCs) regenerates the olfactory neurons. 

Eventually we lose Globose Basal Cells (GBCs) which halts the regeneration of olfactory neurons and results in olfactory loss.
 

A second population of stem cells named Horizontal Basal Cells (HBCs) have the potential to regenerate olfactory neurons, but fail to do so because they are locked in a dormant state.
 

We are developing RNA medicines to activate HBCs to regenerate olfactory neurons and restore olfaction.